Mapping Glycosaminoglycan–Hydroxyapatite Colloidal Gels as Potential Tissue Defect Fillers
نویسندگان
چکیده
منابع مشابه
Mapping Glycosaminoglycan–Hydroxyapatite Colloidal Gels as Potential Tissue Defect Fillers
Malleable biomaterials such as Herschel-Bulkley (H-B) fluids possess shear responsive rheological properties and are capable of self-assembly and viscoelastic recovery following mechanical disruption (e.g., surgical placement via injection or spreading). This study demonstrated that the addition of moderate molecular weight glycosaminoglycans (GAGs) such as chondroitin sulfate (CS) (Mw = 15-30 ...
متن کاملHybrid hydroxyapatite nanoparticle colloidal gels are injectable fillers for bone tissue engineering.
Injectable bone fillers have emerged as an alternative to the invasive surgery often required to treat bone defects. Current bone fillers may benefit from improvements in dynamic properties such as shear thinning during injection and recovery of material stiffness after placement. Negatively charged inorganic hydroxyapatite (HAp) nanoparticles (NPs) were assembled with positively charged organi...
متن کاملOptically transparent dense colloidal gels
Traditionally it has been difficult to study the porous structure of dense colloidal gels and (macro) molecular transport through them simply because of the difference in refractive index between the colloid material and the continuous fluid phase surrounding it, rendering the samples opaque even at low colloidal volume fractions. Here, we demonstrate a novel colloidal gel that can be refractiv...
متن کاملGravitational compression of colloidal gels.
We study the compression of depletion gels under the influence of a gravitational stress by monitoring the time evolution of the gel interface and the local volume fraction, φ, inside the gel. We find φ is not constant throughout the gel. Instead, there is a volume fraction gradient that develops and grows along the gel height as the compression process proceeds. Our results are correctly descr...
متن کاملTuning colloidal gels by shear.
Using a powerful combination of experiments and simulations we demonstrate how the microstructure and its time evolution are linked with mechanical properties in a frustrated, out-of-equilibrium, particle gel under shear. An intermediate volume fraction colloid-polymer gel is used as a model system, allowing quantification of the interplay between interparticle attractions and shear forces. Rhe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Langmuir
سال: 2014
ISSN: 0743-7463,1520-5827
DOI: 10.1021/la4041985